Being the first player, we have what the other player(s) can only dream about: an empty board! So we’d better know our way around this one-and-only time we’ll ever have such chances during the whole game. Let’s try with these tile combinations.
What had we better do, if as the opening player we have this on our rack?
With two big guys (JQ) and two middleweights (FW), this rack is just too heavy (and too much weight will cost us flexibility). When possible, get rid of one of the big guys right away (along with one of the middleweights, sure). So here JAW is quite sensible (If it were T instead of D, then QAT would be even better).